Lessons learned from community engagement regarding phylodynamic research with molecular HIV surveillance data
The widespread implementation of molecular HIV surveillance (MHS) has resulted in an increased discussion about the ethical, human rights and public health implications of MHS. The researchers narrate the process of pausing their research in 2020 to conduct community engagement in response to these growing concerns and summarize the key lessons learned through conversations with community members.
Criminalisation of HIV transmission: implications for public health in Scotland
Article analysing of the first case of HIV transmission in the UK. The authors conclude that far from protecting the public, the judgment has endorsed abrogation of individual responsibility in sexual partnerships by asserting a legal duty of disclosure on the infected partner. It is likely to undermine uptake of HIV testing and risks a one third increase in new HIV infections in Scotland. It also underlines the need for research scientists to anticipate that potentially incriminating results, even in unlabelled studies, may be followed up by forensic requests from individual study participants or by police warrant and recommends an urgent review by the Scottish Executive to minimise the negative effects on public health and molecular science.
HIV-Infected mothers who decide to breastfeed their infants under close supervision in Belgium: About two cases (2020)
A case report from Belgium in which specific guidelines were implemented in order to support two mothers' choice to breastfeed. As a result of different prophylactic measures including antiretrovirals in mothers and infants and close follow-up, none of the infants were infected.
- Alternative links
- Read on the Frontiers Pediatrics site
Mortality in well controlled HIV in the continuous antiretroviral therapy arms of the SMART and ESPRIT trials compared with the general population
Compares mortality rates in well controlled HIV-infected adults in two clinical trials with the general population. Found that HIV-infected individuals on ART with a recent undetectable viral load, who maintained or had recovery of CD4(+) cell counts to at least 500 cells/μl, had no increased risk of death compared with the general population.
Closing the gap: increases in life expectancy among treated HIV-positive individuals in the United States and Canada
Estimates temporal changes in life expectancy among HIV-positive adults on ART from 2000–2007 in the U.S. and Canada. Found a 20-year-old HIV-positive adult on ART could expect to live into their early 70s, a life expectancy approaching that of the general population. Differences by sex, race, HIV transmission risk group, and CD4 count remained.
Life expectancy living with HIV: recent estimates and future implications
Review of the latest literature shows life expectancy of people with HIV has dramatically increased since effective antiretroviral therapy has been available, and it continues to improve. Modelling studies suggest life expectancy could improve further with increased uptake of HIV testing, better antiretroviral regimens and treatment strategies, and the adoption of healthier lifestyles by those living with HIV. Early diagnosis is particularly important.